Who is at risk for acromegaly?

Asked by: Martin Evans  |  Last update: 18 June 2021
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Acromegaly is usually diagnosed in adults aged 30 to 50, but it can affect people of any age. When it develops before the end of puberty, it's known as "gigantism".

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Furthermore, Who is most likely to get acromegaly?

Acromegaly is most often diagnosed in middle-aged adults, but symptoms can appear at any age. In children, too much growth hormone causes a condition called gigantism link rather than acromegaly. Gigantism occurs when excess GH begins before the end of puberty, when children's growth plates fuse or close.

In this regard, What are the risk factors of acromegaly?.
There are no known risk factors for acromegaly other than a prior history of a pituitary tumor.
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Complications:
  • hypopituitarism (too little secretion of other pituitary hormones)
  • high blood pressure.
  • glucose intolerance or diabetes.
  • cardiovascular disease.
  • carpal tunnel syndrome.
  • sleep apnea.
  • arthritis.
  • colonic polyps.


Keeping this in mind, What causes acromegaly?

Acromegaly is a rare disorder that is caused by excess levels of growth hormone (GH) in the body. In most patients, excess levels of GH are causes by a benign (noncancerous) tumor in the pituitary gland (pituitary adenoma).

Who has acromegaly?

Acromegaly affects about 6 per 100,000 people. It is most commonly diagnosed in middle age. Males and females are affected with equal frequency.

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Is acromegaly a disability?

Acromegaly is a disorder in which the pituitary gland produces excess growth hormones. This disabling condition is often caused by a tumor in the pituitary gland.

Is acromegaly inherited?

Usually acromegaly is not inherited. Very rarely, acromegaly is inherited in either a condition called 'familial isolated pituitary adenoma' or as part of multiple endocrine neoplasia type 1 (MEN; see the article on MEN1 for further information).

Can acromegaly be treated?

Acromegaly is a rare but serious medical condition that occurs when the body produces high levels of growth hormone. Acromegaly affects the body's bones and tissues and causes them to grow in abnormal ways. The most common treatments for acromegaly are surgery, medication and radiation therapy.

What is the life expectancy of someone with acromegaly?

Patients who are successfully treated for acromegaly and whose growth hormone and IGF-1 levels fall to normal generally have a normal life expectancy.

What is acromegaly and its signs?

Symptoms of acromegaly include an enlarged face and hands. Changes to the face may cause the brow bone and lower jaw to protrude, and the nose and lips to get larger. Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood.

How can acromegaly be prevented?

Acromegaly cannot be prevented. Early treatment may prevent the disease from getting worse and help avoid complications.

Can symptoms acromegaly reversed?

Acromegaly can be put into remission. This means that the disease is stopped and many of the signs and symptoms reversed. But, acromegaly can be a lifelong disease. Drug and/or radiation therapy typically goes on for several years.

Can acromegaly cause weight gain?

For patients with larger pituitary tumors (typically over 1.5 cm in diameter), there may be symptoms of visual loss from pressure on the optic nerves and optic chiasm, headaches and symptoms of pituitary gland failure (hypopituitarism) including low energy, low libido, loss of menstrual periods in women and weight gain ...

Will I get acromegaly?

Acromegaly is a rare condition where the body produces too much growth hormone, causing body tissues and bones to grow more quickly. Over time, this leads to abnormally large hands and feet, and a wide range of other symptoms. Acromegaly is usually diagnosed in adults aged 30 to 50, but it can affect people of any age.

Is acromegaly an autoimmune disease?

In conclusion, the present study shows a high prevalence of thyroid autoimmunity in acromegaly. Among other pathogenic mechanisms, autoimmunity seems to be an additional factor inducing a high frequency of thyroid disorders in this pituitary disease.

Is acromegaly more common in males or females?

Acromegaly is more common in women who present at an older age with longer diagnostic delay. At presentation, women have a higher GH relative to IGF-1 level than men. QoL is more adversely affected in women both before and after treatment.

What is the most effective cure for acromegaly?

The dopamine agonists used for the therapy of acromegaly include bromocriptine, quinagolide and cabergoline. Cabergoline seems to be the most efficacious of the dopamine agonists for the treatment of acromegaly, with normalization of IGF-I being achieved in up to 35% of patients treated.

Is acromegaly considered a rare disease?

Acromegaly is a chronic rare disease associated with excess growth hormone secretion.